Blog / Codon Anticodon Relationship

Codon–anticodon relationship

Written by Shubhi Khandelwal on Feb 26, 2020

Codon-anticodon relationship is the relationship between the codons of mRNA and anticodons of tRNA to make sure that correct aminoacids are coded from the codons of mRNA.

mRNA contains the nucleotides in triplets that are known as codons. Anticodons are the triplets of nucleotides that are complementary to these codons. The anticodons are present on the tRNA. When tRNA binds to the mRNA, this occurs due to these complementary triplets i.e. due to codon-anticodon relationship. This ensures that correct amino acid is transferred from the tRNA to the mRNA and protein synthesis occurs with the help of desired amino acids.


Key Points

  • Codons and anticodons are complementary to each other
  • Codons on the mRNA bind to the anticodons on the tRNA during protein synthesis.
  • This relationship ensures transfer of correct amino acid from tRNA to mRNA. Thus, a protein with desired amino acids can be formed.

Key Terms

  • proteins: Molecules formed by joining of multiple amino acids (polypeptides).
  • translation: A process occurring in the ribosome, in which a strand of messenger RNA (mRNA) guides the assembly of a sequence of amino acids to make a protein.
  • amino acid: Any organic compound containing both an amino and a carboxylic acid functional group.
  • tRNA: Transfer RNA that transfers amino acids to mRNA

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